You will most likely need to adjust the trim pot, I would suggest doing it by ear. Just set it to move for a long enough time so that you can adjust it while it is in motion. It is much easier than people think if you just listen and feel the motion until it is sounding and moving smoothly. As for orientation goes all the pins should be labeled so just match it up with the old unit that way. You won't burn it out if yo get it in wrong it just won't work.
Printit Industries Model 8.10 fully enclosed CoreXY, Chamber heat
3-SD3's & a Workbench all fully enclosed, RH-Slic3r Win7pro, E3D V6, Volcano & Cyclops Hot End
SSR/500W AC Heated Glass Bed, Linear bearings on SS rods. Direct Drive Y-axis, BulldogXL
Thanks to all for your contributions