well I guess other things are off, because right there changing that setting will make you extrude more then twice as much filament. (I think)
When you changed it, did you select the new filament settings before you sliced? I've confused myself many times when I change a setting, slice, and realize that repetier was still on an old profile.
If you want some settings that work, try these: (keep in mind I'm only listing what values to change, everything I dont mention just leave as you have it the same as me)
on the printer settings / Extruder 1:
Nozzle diameter: .4
Length: 2.5mm
Speed: 150
on print settings / advanced (this is what I suspect is wrong)
change ALL of them to .42 except Support, which I have at .31 so the first six make .42 and the last one .31.
on infill:
fill density: 0.3
fill pattern: honeycomb
solid infill every 0 layers
uncheck retract when crossing perimeters.
on layers and perimeters:
layer height (Whatever you want, though for most parts I use 0.3 unless I'm going for looks)
first later also 0.3000
perimeters 3. (not 75 that's really really wrong!!)
I randomize starting points.
I usually only have 4 solid layers on the top and 3 on the bottom. Its enough and saves some time/material.
Anyway, with all of that you should see a massive improvement because yeah, your settings are /way/ off. And be sure to check the filament settings and make sure they are right. Also, if I remember, the trend for solidoodles is an overcalibrated extruder. (IE it seems to extrude too much, as in 130mm when it should be 100. At least thats what mine and a few I've seen did. Look up how to calibrate it, it helps.)
Let us know how these fixes help! Also please post a screenshot of your filament settings.
Finally one last note. Whenever I change certain things to Zero in slic3r it seems to snap back. So read your settings after you save and make sure they held. If they do not hold, change it to 1 before changing to zero and vice versa, seems to fix for me, once again, has confused me many many times.
Good luck!