Same version. RH 1.0.6 with slic3r 1.2.9.
I copied my settings over to prussa edition to see what would happen. it seems there are a couple more checkboxes. It generated gcode my printer is chugging through right now. Unfortunately things are encased in support so i cant really say what the quality is yet.
While copying settings i noticed that extrusion width for supports was set to 20%. Since most everything seems to be keyed on layer height and im printing at .1mm , I'm assuming it was generating spider silk supports and i didnt have enough vid ram to store all those polygons in previews.
I changed it to .3mm (slightly thinner to the .4mm i have hard coded for most other values now) and it prusa edition generated support in less than a second. I don't know if it was prusa edition or faulty extrusion width. anyway we shall see. Ill report back i next time i print something.
Now i know the software at least kind of sort of works out of box I'm anxious to try the variable layer thickness settings.
(Note: I have the early run sanguinolulu/marlin based solidoodle. i read somewhere the prusa uses same firmware so maybe that's why it seems to be working for me.)
(note2: completely unrelated, but meshmixer auto rotates now on import and export and is overall much more polished than it was when i used it 2 years ago. It is pretty quick and easy to generate the "twig" supports if you prefer that.. i ended up doing that when my large print was crashing out. Also you can create custom printer dimensions now if you want to plate things in advance. It is definitely on my new toy list.)
Thanks for the feedback/suggestions.