Feeding printer filament from other Locations?

I would think that'd be fine, as long as the drag on the filament wasn't drastically increased. The only problem is that the Y-axis motors could skip steps if they have to pull too hard. You could remedy that by using a PTFE tube between the extruder and the back of the SD.

I was thinking about running the PTFE tube all the way from under my desk to at least the back of the SD.  I just cant decide if this will be a hassle in the long run.  My original idea was to have 6 spools of filament mounted under my desk feeding to one opening.  At that point they would run to a junction/holder similar to this http://www.thingiverse.com/thing:19843 where I could simply grab whatever filament I needed and load it into the machine.

I will have to play around with what works.  I don't want the Y-axis skipping though.

You have a link to that cable holder stl pictured there?

Oh wow I thought this was for cables, its specifically for filaments I see.  Is it okay to have your filament just out and about like that? I've been wrapping mine back up in the plastic bags that they come in with the desiccant.

Update:

I have refined the PVC pipe mount for under my desk.  You can now print one of your very own!

On a well calibrated printer it should fit the pipe snug enough to hold it in place. Its a much better fit than the one on the back of the Solidoodle.

Slic3r suggested print settings:
.3mm layers
4 perimeters min
3 top/ 3 bottom
use 50% infill