New to 3D printing (Page 2 of 2)

wardjr wrote:

Acetone is not unsafe, in fact it is naturally created within your own body.  That doesn’t mean you should drink it but skin contact will do nothing more than dry your skin out.
Alcohol will be very ineffective for our application.
Please stick to the facts.

I do biomedical research, I do understand human body create Acetone, Acetone is one of the Ketone bodies liver produced after long term fasting (>24 hours). After long term fasting, liver run out of glycogen and human body start to use fatty acid as energy source but fatty acid can not reach brain, liver create Ketone bodies including acetone that can pass blood-brain barrier and use ketone bodies as energy source.(Low food intake (fasting), carbohydrate restrictive diets, starvation, prolonged intense exercise, alcoholism or in untreated (or inadequately treated) type 1 diabetes mellitus all triger elevated Ketone bodies synthesis.)

However, Acetone concentration produced in human body is very low. And the fact human body only use Ketone bodies and fatty acid only when necessary suggest use these high energy density molecule have adverse effect. The current hypothesis is metabolic these high energy density molecule induce oxidative stress.

Acetone we used in high concentration. We use Acetone treatment in experiment to extract cells or use Acetone/alcohol mixture to fix cell, which means cell dies quickly upon contact with Acetone. Yes, skin contact you don't feel anything because there is a thick layer of dead cell on surface of skin anyway. However, Acetone contact will extract all lipid and nuclear acid and most of cellular content away from those dead cell and they become white in color. In areas that is not as well protected by dead cell, it will kill alive cells. example are eye, ear, inside of mouth, nose, etc.

Since Acetone is one of the alternative energy source for brain, it will regulate brain metabolism when in low physiological concentration. On the other hand, it will mess up brain metabolism when in high concentration, it will behave as depress the central nervous system in short term and potential metabolic mis-regulation in long term. People with metabolic mis-regulation condition are more vulnerable including diabetic condition and obesity condition. Human body also evolved to deal with ketone bodies(acetoacetate, beta-hydroxybutyrate, and acetone) at certain ratio, elevated acetone level alone without corresponding acetoacetate and beta-hydroxybutyrate increase also lead to mis-regulated metabolism.

With that said, although acetone is believed to exhibit only slight toxicity in normal use, it is not safe to use without proper protection.

Please read the cited source in case I express anything wrong with my poor English.

https://en.wikipedia.org/wiki/Ketone_bo … the_liver)

https://en.wikipedia.org/wiki/Acetone

https://www.des.nh.gov/organization/com … -ehp-7.pdf

The bottom line is use acetone is not that safe. It is recommended to use alcohol or soapy water to clean the lipid or grease.

When people had adverse effect on Acetone, they did not drink or bath in it, Acetone evaporate fast and people uptake Acetone by breath Acetone vapor.

I'm sure most people can read the cautions on a container and will download and read the MSDS. I also trust people will not test the safety by skin contact or breath the vapor. I wrote the wall of text to improve my scientific writing in English and you can ignore it if you already know every detail of it.

always have to have a come back