40 years old is still very young, persistent tickle in your throat are signs of in Inflammation, can cause by from auto-immune disease like Asthma to throat cancer. If you are not smoking or humidity in your room is not extremely low, you need to see doctor. Flu or allergy may also cause this but usually don't last more than two to three weeks.
Inflammation usually triggered by exogenous DNA, RNA, and protein, which is not significant in pollution produced by 3D printer. unless your filament have mold growing on them.
Chronic Inflammation is something you should be concerned/worried about, go see doctor.
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