If you want a fully enclosed 3d printer they are available but IMHO a bit pricey .
the Up mini and the up mini 2 are available from tier time  or other internet vendors
Here is a link to the latest mini model

https://store.tiertime.com/collections/ … -mini-2-es

Current msrp $699 this is for a 4.75 x 4.75  build volume machine

This comes with a HEPA filter and a carbon filter a door safety switch and a filament can that protect  from moisture.

https://www.tiertime.com/up-box-plus/
This one has a 205 mm square print bed  aprox 8 x 8 inch a built in spool hold and all the bells and whistles of the mini model.

Current MSRP $1899
These printer have a good reputation   

If you want one on these please do your research. prices and features vary depending on exact model. watch several reviews on you tube. This is information not a recommendation for or against this product.

That  being said I know of no one on this forum that has a printer of this type ((Fully enclosed filtered system). Most of us here have several printers may are in common living spaces a shop off the kitchen , dinning room , living room or bedroom. 
And there are no know health issues  from these printers. I stick pretty much to pla. I have printed a little in PET.

Yes these are availble as well but cost as much as a 3d printer.
https://www.printedsolid.com/collection … 8337090572

Again this is your choice   there are commercially available enclosures and filtration systems and plenty of the right kind of filter to build your own. Again do your homework.

Any machines that don't let any nanoparticles leave the machine during the building process? Totally sealed?

that would be a very expensive machine to make and buy. Most people just put them in a sealed enclosure if they have medical issues and need to vent the fumes to the outside. But honestly unless you are printing nylon or burning ABS the release from the machine is near harmless unless you or those around have a medical condition that makes you sensitive. I have a 600 sqft apartment and my printer is in my bed room and often prints when I am asleep. I have had it this way for more than 5 years and have not had any ill effects from the printing.

By the way, nanoparticles don't exist outside of a lab yet. At best they are microparticles if they are particles at all. It's mostly just smell and fumes and the fumes come in when your temp is too high.